CTLA4 Antikörper (iFluor™488)
Kurzübersicht für CTLA4 Antikörper (iFluor™488) (ABIN7539512)
Target
Alle CTLA4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
- CD152 iFluor488 Antibody
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Produktmerkmale
- The clone A3.4H2, a mouse monoclonal antibody, selectively binds to the human 33- kDa member of the immunoglobulin superfamily, also known as Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4). CD152 is a protein receptor that functions as an immune checkpoint and downregulates immune responses. It is transiently expressed on activated CD28+ T cells and binds to CD80 and CD86 present on antigen presenting cells (APC) with high avidity. Intracellular CD152 is also expressed on regulatory T cells and contributes to their inhibitory function.
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Aufreinigung
- Purified
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Reinheit
- >95 %
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Immunogen
- Activated T cells
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Isotyp
- IgG2a, kappa
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Applikationshinweise
- FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2-8°C, Conjugated antibodies should never be frozen.
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- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
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Andere Bezeichnung
- CD152
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Gen-ID
- 929
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UniProt
- P08571
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Pathways
- Cancer Immune Checkpoints
Target
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