CD40 Antikörper (Biotin)

Produktnummer ABIN7456693

Der Maus Monoklonal Anti-CD40-Antikörper wurde für FACS validiert. Er ist geeignet, CD40 in Proben von Human zu detektieren.

Kurzübersicht für CD40 Antikörper (Biotin) (ABIN7456693)

Target: CD40

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD40 Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS)

Klon: G28-5

Produktdetails anti-CD40 Antikörper (Biotin)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Kommentare:

Matching Isotype Control: Biotin Mouse IgG1, κ Isotype Control[MOPC-21] (ABIN7469769)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % Protein protectant

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2~8°C. Do not freeze.

Details zu CD40

Target: CD40

Andere Bezeichnung: CD40

Hintergrund: Bp50,CDw40,CD40L receptor,TNFRSF5,CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand).

Gen-ID: 958

UniProt: P25942

Pathways: NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints