MAP2K7 Antikörper (AA 1-50)
Kurzübersicht für MAP2K7 Antikörper (AA 1-50) (ABIN7455014)
Target
Alle MAP2K7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-50
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Verwendungszweck
- Rabbit anti-MKK7 Antibody, Affinity Purified
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Homologie
- Rat
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 1 and 50
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))
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Andere Bezeichnung
- MKK7
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Hintergrund
- Background: MAP kinase kinase 7 (MKK7) is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. MKK7 is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stress [taken from NCBI Entrez Gene (Gene ID: 5609)].
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Gen-ID
- 5609
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NCBI Accession
- NP_660186
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UniProt
- O14733
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Pathways
- MAPK Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling
Target
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