CDK8 Antikörper (AA 420-470)
Kurzübersicht für CDK8 Antikörper (AA 420-470) (ABIN7453676)
Target
Alle CDK8 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 420-470
-
Verwendungszweck
- Rabbit anti-CDK8 Antibody, Affinity Purified
-
Homologie
- Mouse
-
Aufreinigung
- Affinity Purified
-
Immunogen
- between AA 420 and 470
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 200 μg/mL
-
Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
-
Andere Bezeichnung
- CDK8
-
Hintergrund
- Background: Cyclin-dependent kinase 8 (CDK8) associates with cyclin C and is a component of the RNA polymerase II holoenzyme complex which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. CDK8 has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery [taken from NCBI Entrez Gene (GeneID: 1024)].
-
Gen-ID
- 1024
-
NCBI Accession
- NP_001251
-
UniProt
- P49336
-
Pathways
- Zellzyklus, Regulation of Lipid Metabolism by PPARalpha
Target
-