CDK8 Antikörper

Produktnummer ABIN7266596

Der Kaninchen Monoklonal anti-CDK8 Antikörper wird verwendet zum Nachweis von CDK8 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für CDK8 Antikörper (ABIN7266596)

Target: CDK8 (Cyclin-Dependent Kinase 8 (CDK8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CDK8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CDK8 Antikörper

Verwendungszweck: CDK8 Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human CDK8

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CDK8

Target: CDK8 (Cyclin-Dependent Kinase 8 (CDK8))

Andere Bezeichnung: CDK8

Hintergrund: This gene encodes a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit, cyclin C, are components of the Mediator transcriptional regulatory complex, involved in both transcriptional activation and repression by phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II. This kinase regulates transcription by targeting the cyclin-dependent kinase 7 subunits of the general transcription initiation factor IIH, thus providing a link between the Mediator complex and the basal transcription machinery. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016],K35,Cell Biology & Developmental Biology,Cell Cycle,Epigenetics & Nuclear Signaling,Kinase,Kinase_Serine/threonine kinases,Notch Signaling Pathway,Signal Transduction,Wnt/β-Catenin Signaling Pathway,CDK8

Molekulargewicht: 53kDa

Gen-ID: 1024

UniProt: P49336

Pathways: Zellzyklus, Regulation of Lipid Metabolism by PPARalpha