CDK8 Antikörper (AA 370-420)
Kurzübersicht für CDK8 Antikörper (AA 370-420) (ABIN7451212)
Target
Alle CDK8 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 370-420
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Verwendungszweck
- Rabbit anti-CDK8 Antibody, Affinity Purified
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Homologie
- Mouse,X. laevis,X. tropicalis
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 370 and 420
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: Not recommended. Use rabbit anti-CDK8 antibody ABIN7453676.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
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Andere Bezeichnung
- CDK8
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Hintergrund
- Background: Cyclin-dependent kinase 8 (CDK8) associates with cyclin C and is a component of the RNA polymerase II holoenzyme complex which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. CDK8 has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery [taken from NCBI Entrez Gene (GeneID: 1024)].
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Gen-ID
- 1024
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NCBI Accession
- NP_001251
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UniProt
- P49336
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Pathways
- Zellzyklus, Regulation of Lipid Metabolism by PPARalpha
Target
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