TAB3 Antikörper (AA 600-650)

Produktnummer ABIN7450797

Produktdetails anti-TAB3 Antikörper

Target: TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))

Bindungsspezifität: AA 600-650

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-TAB3 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 600 and 650

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu TAB3

Target: TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))

Andere Bezeichnung: TAB3 (TAB3 Produkte)

Synonyme: MAP3K7IP3 antikoerper, NAP1 antikoerper, 4921526G09Rik antikoerper, Map3k7ip3 antikoerper, mKIAA4135 antikoerper, map3k7ip3 antikoerper, nap1 antikoerper, tab3 antikoerper, tab3-a antikoerper, tab3-b antikoerper, map3k7ip3l antikoerper, si:ch211-232d19.8 antikoerper, si:dkey-30h22.6 antikoerper, TGF-beta activated kinase 1 and MAP3K7 binding protein 3 antikoerper, TGF-beta activated kinase 1/MAP3K7 binding protein 3 antikoerper, TGF-beta activated kinase 1/MAP3K7 binding protein 3 S homeolog antikoerper, TAB3 antikoerper, Tab3 antikoerper, tab3.S antikoerper, tab3 antikoerper

Hintergrund: Background: TAK1-binding protein 3 (TAB3) is a binding and regulatory subunit of the transforming growth factor-beta-activated kinase 1 (TAK1). TAB3 functions as an adaptor that mediates IL1 and TNF signaling pathways. Additionally it plays a role in the activation of the NF-kappaB pathway by functioning as receptors that bind polyubiquitin chains for the regulation of kinase activity.

Gen-ID: 257397

NCBI Accession: NP_690000

UniProt: Q8N5C8

Pathways: TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades