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JAK2 Antikörper (AA 1082-1132)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch JAK2 in IHC. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7448611

Kurzübersicht für JAK2 Antikörper (AA 1082-1132) (ABIN7448611)

Target

Alle JAK2 Antikörper anzeigen
JAK2 (Janus Kinase 2 (JAK2))

Reaktivität

  • 152
  • 95
  • 91
  • 19
  • 18
  • 3
  • 2
  • 2
  • 1
Human

Wirt

  • 163
  • 5
  • 1
Kaninchen

Klonalität

  • 148
  • 21
Polyklonal

Konjugat

  • 94
  • 13
  • 7
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Dieser JAK2 Antikörper ist unkonjugiert

Applikation

  • 131
  • 75
  • 66
  • 52
  • 29
  • 27
  • 27
  • 24
  • 22
  • 20
  • 10
  • 4
  • 4
  • 2
  • 1
  • 1
Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 30
    • 28
    • 16
    • 16
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1082-1132

    Verwendungszweck

    Rabbit anti-JAK2 IHC Antibody, Affinity Purified

    Homologie

    Dog,Horse,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Northern white-cheeked gibbon,Naked mole rat,Ferret

    Aufreinigung

    Affinity Purified

    Immunogen

    Between AA 1082 and 1132

    Isotyp

    IgG
  • Applikationshinweise

    1:100 - 1:500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    250 μg/mL

    Buffer

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Haltbarkeit

    12 months
  • Target

    JAK2 (Janus Kinase 2 (JAK2))

    Andere Bezeichnung

    JAK2

    Hintergrund

    Background: JAK2 (Janus kinase 2) was originally cloned via screening of mouse cDNA libraries with PCR generated probes representing highly conserved elements in the protein tyrosine kinase (PTK) family. JAK2, as well as JAK, was named after the Roman god, Janus, the god of gates or doors, and who is depicted as having two faces which face opposite directions. JAK kinases bear two nearly identical phosphate transferring domains and function to transduce signals from type I and type II cytokine receptors for the activation of STAT (signal transducers and activators of transcription) transcription factors.

    Gen-ID

    3717

    NCBI Accession

    NP_004963

    UniProt

    O60674

    Pathways

    JAK-STAT Signalweg, RTK Signalweg, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
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