BRAF Antikörper (AA 25-75)
Kurzübersicht für BRAF Antikörper (AA 25-75) (ABIN7448439)
Target
Alle BRAF Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 25-75
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Verwendungszweck
- Rabbit anti-BRAF IHC Antibody, Affinity Purified
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Homologie
- Mouse,Rat,Bovine,Dog,Gorilla,Chimpanzee,Crab-eating macaque,White-tufted-ear marmoset,Northern white-cheeked gibbon,Small-eared galago
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 25 and 75
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Isotyp
- IgG
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Applikationshinweise
- 1:100 - 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 100 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))
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Andere Bezeichnung
- BRAF
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Hintergrund
- Background: B-Raf proto-oncogene serine/threonine-protein kinase (BRAF) is a member of the raf/mil family of serine/threonine kinases. BRAF is involved in transducing mitogenic signals via the MAP kinase/ERKs signaling pathway. Mutations in BRAF are involved in a wide range of cancers such as lung, non-Hodgkin lymphoma, and colorectal cancer. Defects in BRAF are also the cause of cardiofaciocutaneous syndrome (CFC), an autosomal dominant syndrome characterized by facial anomalies, heart defects, and ectodermal abnormalities.
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Gen-ID
- 673
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NCBI Accession
- NP_004324
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UniProt
- P15056
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Pathways
- MAPK Signalweg, RTK Signalweg, Neurotrophin Signalübertragung, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagie
Target
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