NFATC1 Antikörper

Produktnummer ABIN7268976

Dieses Anti-NFATC1-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von NFATC1 in WB. Geeignet für Human.

Kurzübersicht für NFATC1 Antikörper (ABIN7268976)

Target: NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser NFATC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NFATC1 Antikörper

Verwendungszweck: NFAT2 Rabbit mAb

Kreuzreaktivität: Human

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human NFAT2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NFATC1

Target: NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))

Andere Bezeichnung: NFATC1

Hintergrund: The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq, Jul 2013],NF-ATC,NF-ATc1.2,NFAT2,NFATc,NFATC1,B Cell Receptor Signaling Pathway,Cardiovascular,Epigenetics & Nuclear Signaling,Heart,Heart_Cardiogenesis,Immunology & Inflammation,MAPK-JNK Signaling Pathway,Signal Transduction,T Cell Receptor Signaling Pathway,Transcription Factors,NFATC1

Molekulargewicht: 101kDa

Gen-ID: 4772

UniProt: O95644

Pathways: RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung