NRF2 Antikörper (pSer40)
Kurzübersicht für NRF2 Antikörper (pSer40) (ABIN7268970)
Target
Alle NRF2 (NFE2L2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer40
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Verwendungszweck
- Phospho-NRF2-S40 Rabbit mAb
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Phosphorylated Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A phospho specific peptide corresponding to residues surrounding S40 of human NRF2
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
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Andere Bezeichnung
- NFE2L2
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Hintergrund
- This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters, many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015],HEBP1, NRF2,Cardiovascular,Cell Biology & Developmental Biology,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Heart,Heart_Cardiac metabolism,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial Biogenesis,Nucleotide metabolism,Nucleotide metabolism_Molecular processes,Transcription Factors,NFE2L2
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Molekulargewicht
- 90kDa
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Gen-ID
- 4780
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UniProt
- Q16236
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Pathways
- ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
Target
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