JAK2 Antikörper (pTyr221)

Produktnummer ABIN7221936

Dieser Anti-JAK2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von JAK2 in WB, ELISA und IHC (p). Geeignet für Human, Ratte und Maus.

Kurzübersicht für JAK2 Antikörper (pTyr221) (ABIN7221936)

Target: JAK2 (Janus Kinase 2 (JAK2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JAK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-JAK2 Antikörper

Bindungsspezifität: pTyr221

Verwendungszweck: JAK2 (phospho Tyr221) Polyclonal Antibody

Spezifität: Phospho-JAK2 (Y221) Polyclonal Antibody detects endogenous levels of JAK2 protein only when phosphorylated at Y221.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human JAK2 Phospho-Tyr221

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu JAK2

Target: JAK2 (Janus Kinase 2 (JAK2))

Andere Bezeichnung: JAK2

Hintergrund: Rabbit Anti-JAK2 (phospho Tyr221) Polyclonal Antibody,JAK2, Tyrosine-protein kinase JAK2, Janus kinase 2, JAK-2,JAK2 product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.,Tyrosine-protein kinase JAK2

Molekulargewicht: observerd band 130kDa

Gen-ID: 3717

UniProt: O60674

Pathways: JAK-STAT Signalweg, RTK Signalweg, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response