FOXO1 Antikörper (pThr24, pThr32)

Produktnummer ABIN7220640

Der Kaninchen Polyklonal anti-FOXO1 Antikörper wird verwendet zum Nachweis von FOXO1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA und IHC (p).

Kurzübersicht für FOXO1 Antikörper (pThr24, pThr32) (ABIN7220640)

Target: FOXO1 (Forkhead Box O1 (FOXO1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-FOXO1 Antikörper

Bindungsspezifität: pThr24, pThr32

Verwendungszweck: FoxO1/3/4 (phospho Thr24/32) Polyclonal Antibody

Spezifität: Phospho-FoxO1/3/4 (T24/32) Polyclonal Antibody detects endogenous levels of FoxO1/3/4 protein only when phosphorylated at T24/32.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human FoxO1/3/4 Phospho-Thr24/32

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu FOXO1

Target: FOXO1 (Forkhead Box O1 (FOXO1))

Andere Bezeichnung: FoxO1/3/4

Hintergrund: Rabbit Anti-FoxO1/3/4 (phospho Thr24/32) Polyclonal Antibody,FOXO1, FKHR, FOXO1A, Forkhead box protein O1, Forkhead box protein O1A, Forkhead in rhabdomyosarcoma, FOXO3, FKHRL1, FOXO3A, Forkhead box protein O3, AF6q21 protein, Forkhead in rhabdomyosarcoma-like 1, FOXO4, AFX, AFX1, MLLT7, Forkhead box,FOXO1 belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined, however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.,Forkhead box protein O1

Molekulargewicht: observerd band 78kDa

Gen-ID: 2308, 4303

Pathways: PI3K-Akt Signalweg, Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling