AXL Antikörper

Produktnummer ABIN7223506

Der Kaninchen Polyklonal anti-AXL Antikörper wird verwendet zum Nachweis von AXL in Proben von Human, Maus und Ratte. Er wurde validiert für ELISA, IHC und IF.

Kurzübersicht für AXL Antikörper (ABIN7223506)

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AXL Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-AXL Antikörper

Verwendungszweck: Rabbit Anti-Axl Polyclonal Antibody

Spezifität: Axl Polyclonal Antibody detects endogenous levels of Axl protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Axl around the non-phosphorylation site of Y697

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu AXL

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Andere Bezeichnung: Axl

Hintergrund: AXL, UFO, Tyrosine-protein kinase receptor UFO, AXL oncogeneThe protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). AXL may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of AXL.

Molekulargewicht: 130kD

Gen-ID: 558

UniProt: P30530

Pathways: RTK Signalweg, Cellular Response to Molecule of Bacterial Origin