AXL Antikörper (pTyr691)

Produktnummer ABIN7223504

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch AXL in WB, ELISA und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für AXL Antikörper (pTyr691) (ABIN7223504)

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AXL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-AXL Antikörper

Bindungsspezifität: pTyr691

Verwendungszweck: Axl (phospho Tyr691) Polyclonal Antibody

Spezifität: Phospho-Axl (Y691) Polyclonal Antibody detects endogenous levels of Axl protein only when phosphorylated at Y691.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Axl Phospho-Tyr691

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu AXL

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Andere Bezeichnung: Axl

Hintergrund: Rabbit Anti-Axl (phospho Tyr691) Polyclonal Antibody,AXL, UFO, Tyrosine-protein kinase receptor UFO, AXL oncogene,The protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). AXL may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of AXL.,Tyrosine-protein kinase receptor UFO

Gen-ID: 558

UniProt: P30530

Pathways: RTK Signalweg, Cellular Response to Molecule of Bacterial Origin