CD11b Antikörper (AA 623-728)
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- Target Alle CD11b (ITGAM) Antikörper anzeigen
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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Bindungsspezifität
- AA 623-728
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD11b Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), ELISA
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human ITGAM (AA: 623-728) expressed in E. coli.
- Klon
- 3A4B10
- Isotyp
- IgG1
- Top Product
- Discover our top product ITGAM Primärantikörper
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- Applikationshinweise
- WB:1:500 - 1:2000, IHC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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- Target
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- Andere Bezeichnung
- ITGAM (ITGAM Produkte)
- Synonyme
- CD11b/CD18 antikoerper, CR3 antikoerper, CR3A antikoerper, Cd11b antikoerper, F730045J24Rik antikoerper, Ly-40 antikoerper, MAC1 antikoerper, Mac-1 antikoerper, Mac-1a antikoerper, CD11B antikoerper, MAC-1 antikoerper, MAC1A antikoerper, MO1A antikoerper, SLEB6 antikoerper, C3bi antikoerper, integrin subunit alpha M antikoerper, integrin alpha M antikoerper, integrin, alpha M (complement component 3 receptor 3 subunit) antikoerper, integrin alpha-M antikoerper, ITGAM antikoerper, Itgam antikoerper, LOC100351865 antikoerper
- Hintergrund
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Description: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
Aliases: CR3A, MO1A, CD11B, MAC-1, MAC1A, SLEB6
- Molekulargewicht
- 127.1 kDa
- Gen-ID
- 3684
- Pathways
- Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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