TRADD Antikörper (AA 1-177)
Kurzübersicht für TRADD Antikörper (AA 1-177) (ABIN7193412)
Target
Alle TRADD Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-177
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Verwendungszweck
- TRADD Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human TRADD (AA: 1-177) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
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Andere Bezeichnung
- TRADD
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Hintergrund
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The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]
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Molekulargewicht
- 34.2 kDa
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Gen-ID
- 8717
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UniProt
- Q15628
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Pathways
- NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Hepatitis C
Target
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