TLR9 Antikörper (AA 26-193)

Produktnummer ABIN7193346

Dieses Anti-TLR9-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von TLR9 in ELISA und FACS. Geeignet für Human.

Kurzübersicht für TLR9 Antikörper (AA 26-193) (ABIN7193346)

Target: TLR9 (Toll-Like Receptor 9 (TLR9))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TLR9 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Klon: 5B10E8

Produktdetails anti-TLR9 Antikörper

Bindungsspezifität: AA 26-193

Verwendungszweck: CD289 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CD289 (AA: 26-193) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu TLR9

Target: TLR9 (Toll-Like Receptor 9 (TLR9))

Andere Bezeichnung: CD289

Hintergrund:

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.

Molekulargewicht: 116 kDa

UniProt: Q9NR96

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades