LRP6 Antikörper (AA 1198-1370)
Kurzübersicht für LRP6 Antikörper (AA 1198-1370) (ABIN7193277)
Target
Alle LRP6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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    - 
                                            Bindungsspezifität
- AA 1198-1370
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                                            Verwendungszweck
- LRP6 Antibody
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                                            Aufreinigung
- Purified antibody
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                                            Immunogen
- Purified recombinant fragment of human LRP6 (AA: 1198-1370) expressed in E. Coli.
- 
                                            Isotyp
- IgG1
 
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    - 
                                            Applikationshinweise
- 
                        ELISA: 1/10000 FCM: 1/200 - 1/400 
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
- 
                                            Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            Lagerung
- 4 °C,-20 °C
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                                            Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
 
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    - LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
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                                            Andere Bezeichnung
- LRP6
- 
                                            Hintergrund
- 
                        This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined. 
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                                            Molekulargewicht
- 180 kDa
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                                            UniProt
- O75581
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                                            Pathways
- WNT Signalweg, Tube Formation
 Target
- 
                    
 
                                     
                                     
                                    