FADD Antikörper (C-Term)

Produktnummer ABIN7180169

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FADD in WB und ELISA. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für FADD Antikörper (C-Term) (ABIN7180169)

Target: FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FADD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-FADD Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Human, Maus

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human FADD.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FADD

Target: FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))

Andere Bezeichnung: Fadd/FADD

Hintergrund:

Background: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis By similarity. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling By similarity.

Zhang J., Mol. Cell. Biol. 16:2756-2763(1996).
Hsu H., Cell 84:299-308(1996).
Carninci P., Science 309:1559-1563(2005)

Aliases: Fadd antibody, Mort1FAS-associated death domain protein antibody, FAS-associating death domain-containing protein antibody, Mediator of receptor induced toxicity antibody, Protein FADD antibody

UniProt: Q61160

Pathways: Apoptose, TLR Signalweg, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades