VAV1 Antikörper (Tyr174)
Kurzübersicht für VAV1 Antikörper (Tyr174) (ABIN7180104)
Target
Alle VAV1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Tyr174
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized non-phosphopeptide derived from Human VAV1 around the phosphorylation site of tyrosine 174 (E-I-Y-E-D).
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Isotyp
- IgG
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Applikationshinweise
- WB:1:500-1:3000, IHC:1:50-1:100,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- VAV1 (Vav 1 Oncogene (VAV1))
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Andere Bezeichnung
- VAV1
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Hintergrund
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Background: Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
Ana V. Miletic, J. Biol. Chem., Dec 2006, 281: 38257 - 38265.
Christopher C. Stebbins, Mol. Cell. Biol., Sep 2003, 23: 6291 - 6299.
Vered Schapira, Cancer Res., Jun 2006, 66: 6183 - 6191.
Maya Groysman, J. Biol. Chem., Dec 2002, 277: 50121 - 50130.Aliases: Oncogene vav antibody, p95Vav antibody, Proto-oncogene vav antibody, Protooncogene vav antibody, VAV 1 antibody, VAV 1 oncogene antibody, VAV antibody, Vav proto oncogene antibody, VAV_HUMAN antibody, VAV1 antibody
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UniProt
- P15498
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Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, CXCR4-mediated Signaling Events, BCR Signaling
Target
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