Angiotensin I Converting Enzyme 1 Antikörper (AA 1046-1263)

Produktnummer ABIN7178777

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Angiotensin I Converting Enzyme 1 in IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Ratte.

Kurzübersicht für Angiotensin I Converting Enzyme 1 Antikörper (AA 1046-1263) (ABIN7178777)

Target: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Angiotensin I Converting Enzyme 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-Angiotensin I Converting Enzyme 1 Antikörper

Bindungsspezifität: AA 1046-1263

Verwendungszweck: Ace Antibody

Kreuzreaktivität: Ratte

Aufreinigung: Protein G purified

Reinheit: >95 %

Immunogen: Recombinant Rat Angiotensin-converting enzyme protein (1046-1263AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Angiotensin I Converting Enzyme 1

Target: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Andere Bezeichnung: Ace

Hintergrund:

Background: Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. This GPIase activity seems to be crucial for the egg-binding ability of the sperm (By similarity).

Aliases: Ace antibody, Dcp1 antibody, Angiotensin-converting enzyme antibody, ACE antibody, EC 3.2.1.- antibody, EC 3.4.15.1 antibody, Dipeptidyl carboxypeptidase I antibody, Kininase II antibody, CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme antibody, soluble form] antibody

UniProt: P47820

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration