Angiotensin I Converting Enzyme 1 Antikörper

Produktnummer ABIN6939231

Produktdetails anti-Angiotensin I Converting Enzyme 1 Antikörper

Target: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Angiotensin I Converting Enzyme 1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Coating (Coat), Staining Methods (StM)

Aufreinigung: Purified by Protein A/G

Immunogen: Full-length recombinant human ACE/CD143 protein

Klon: 9B9

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate.

Known Application: ELISA (For coating, order antibody without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) ,(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Angiotensin I Converting Enzyme 1

Target: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Andere Bezeichnung: ACE (ACE Produkte)

Synonyme: ACE1 antikoerper, CD143 antikoerper, DCP antikoerper, DCP1 antikoerper, ICH antikoerper, MVCD3 antikoerper, AW208573 antikoerper, Dcp1 antikoerper, StsRR92 antikoerper, dcp antikoerper, ace1 antikoerper, dcp1 antikoerper, xace antikoerper, cd143 antikoerper, ACE antikoerper, angiotensin I converting enzyme antikoerper, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 antikoerper, angiotensin-converting enzyme antikoerper, angiotensin I converting enzyme (peptidyl-dipeptidase A) 3 antikoerper, angiotensin-converting enzyme-like antikoerper, ACE antikoerper, Ace antikoerper, ace antikoerper, CpipJ_CPIJ009106 antikoerper, ACE3 antikoerper, LOC101824864 antikoerper

Hintergrund: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

Molekulargewicht: 195kDa

Gen-ID: 1636

UniProt: P12821

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration