Angiotensin I Converting Enzyme 1 Antikörper (AA 30-270)

Produktnummer ABIN3016740

Der Kaninchen Polyklonal anti-Angiotensin I Converting Enzyme 1 Antikörper wird verwendet zum Nachweis von Angiotensin I Converting Enzyme 1 in Proben von Human. Er wurde validiert für WB und IHC.

Kurzübersicht für Angiotensin I Converting Enzyme 1 Antikörper (AA 30-270) (ABIN3016740)

Target: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Angiotensin I Converting Enzyme 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Angiotensin I Converting Enzyme 1 Antikörper

Bindungsspezifität: AA 30-270

Sequenz: EASQQVTVTH GTSSQATTSS QTTTHQATAH QTSAQSPNLV TDEAEASKFV EEYDRTSQVV WNEYAEANWN YNTNITTETS KILLQKNMQI ANHTLKYGTQ ARKFDVNQLQ NTTIKRIIKK VQDLERAALP AQELEEYNKI LLDMETTYSV ATVCHPNGSC LQLEPDLTNV MATSRKYEDL LWAWEGWRDK AGRAILQFYP KYVELINQAA RLNGYVDAGD SWRSMYETPS LEQDLERLFQ E

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-270 of human ACE11 (NP_690043.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Angiotensin I Converting Enzyme 1

Target: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Andere Bezeichnung: ACE

Hintergrund: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.,ACE,ACE1,CD143,DCP,DCP1,angiotensin-converting enzyme,ICH,MVCD3,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Ubiquitin,Endocrine & Metabolism,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,Cardiovascular,Blood,Serum Proteins,Hypoxia,ACE

Molekulargewicht: 78 kDa/83 kDa/131 kDa/149 kDa

Gen-ID: 1636

UniProt: P12821

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration