CD11b Antikörper (FITC)

Produktnummer ABIN7178495

Dieser Maus Monoklonal Antikörper erkennt spezifisch CD11b in FACS, IF und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD11b Antikörper (FITC) (ABIN7178495)

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD11b Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), ELISA

Produktdetails anti-CD11b Antikörper (FITC)

Verwendungszweck: ITGAM Monoclonal Antibody,FITC Conjugated

Aufreinigung: Affinity purified

Immunogen: Recombinant Protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09 % sodium azide and 0.2 % (w/v) BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Andere Bezeichnung: ITGAM

Hintergrund:

Background: 4AM216 reacts with CD11b, a member of the integrin a chain family with 165 kDa MW. which is expressed on NK cells, monocytes, granulocytes and subsets of T and B cells. It associates with CD18 to form CD11b/CD18 complex .The cellular function of CD11b is on neutrophil and monocyte interactions with stimulated endothelium; Phagocytosis of iC3b or IgG coated particles as a receptor; Chemotaxis and apoptosis.* CD11b is absent in Leukocyte Adhesion Deficiency (LAD-1) patients who have major problems with bacterial infections.This clone is cross reactive with non-human primate.1. Ling NR  et al., eds. (1987) Leucocyte Typing  III : White Cell Differentiation Antigens, Oxford University Press, New York. 303-3342. Petty HR nd Todd RF. (1996) Immunol. Today 17:2093. Springer TA (1994) Cell 76:3014. Stewart M et al (1995) Curr Opin Cell Biol 7:690

Aliases: N/A

UniProt: P11215

Pathways: Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation