CD14 Antikörper (PE-Cy5)

Produktnummer ABIN7178400

Der Maus Monoklonal Anti-CD14 Antikörper wurde für FACS, IF und ELISA validiert. Er ist geeignet, CD14 in Proben von Human zu detektieren.

Kurzübersicht für CD14 Antikörper (PE-Cy5) (ABIN7178400)

Target: CD14

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD14 Antikörper ist konjugiert mit PE-Cy5

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), ELISA

Produktdetails anti-CD14 Antikörper (PE-Cy5)

Verwendungszweck: CD14 Monoclonal Antibody,PE-Cy5 Conjugated

Aufreinigung: Affinity purified

Immunogen: Recombinant Protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09 % sodium azide and 0.2 % (w/v) BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CD14

Target: CD14

Andere Bezeichnung: CD14

Hintergrund:

Background: 4AW4 reacts with CD14, a 53-55 kDa molecule. CD14 is a human high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS-endotoxin) and serum LPS-binding protein (LPB). CD14 antigen has a strong presence on the surface of monocytes/macrophages, is weakly expressed on granulocytes, but not expressed by myeloid progenitor cells. CD14 functions as a receptor for endotoxin; when the monocytes become activated they release cytokines such as TNF, and up-regulate cell surface molecules including adhesion molecules.This clone is cross reactive with non-human primate.1. Knapp, W et al., eds. (1989)  Leucocyte Typing  IV: White Cell Differentiation Antigens, Oxford University Press, New York.2. Makgoba, MW et al., (1988)  Nature  331: 86-883. Boyd. AW et al. (1989) Blood 73: 1896-1903

Aliases: N/A

UniProt: P08571

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades