RASGRF1 Antikörper (pSer929) (Cy3)

Produktnummer ABIN713204

Der Kaninchen Polyklonal Anti-RASGRF1-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, RASGRF1 in Proben von Ratte zu detektieren.

Kurzübersicht für RASGRF1 Antikörper (pSer929) (Cy3) (ABIN713204)

Target: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASGRF1 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-RASGRF1 Antikörper (Cy3)

Bindungsspezifität: pSer929

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human RasGRF1 around the phosphorylation site of Ser929

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu RASGRF1

Target: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Andere Bezeichnung: RASGRF1

Hintergrund:

Synonyms: RASGRF1phospho S929, RASGRF1phospho Ser929, p-RASGRF1S929, p-RASGRF1Ser929, CDC25, CDC25L, GNRP, GRF1, GRF55, Guanine nucleotide exchange factor, Guanine nucleotide releasing factor 55 kD, Guanine nucleotide releasing protein, HGRF55, PP13187, Ras protein specic guanine nucleotide releasing factor 1, Ras specic guanine nucleotide releasing factor, Ras specic guanine nucleotide releasing factor CDC25 homolog, Ras specic nucleotide exchange factor CDC25.

Background: The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]

Gen-ID: 5923

Pathways: RTK Signalweg, Zellzyklus, M Phase