Patched 1 Antikörper (AA 1180-1411) (Biotin)

Produktnummer ABIN7165904

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Patched 1 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Patched 1 Antikörper (AA 1180-1411) (Biotin) (ABIN7165904)

Target: Patched 1 (PTCH1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Patched 1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-Patched 1 Antikörper (Biotin)

Bindungsspezifität: AA 1180-1411

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Protein patched homolog 1 protein (1180-1411AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Patched 1

Target: Patched 1 (PTCH1)

Andere Bezeichnung: PTCH1

Hintergrund:

Background: Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog\'s proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.

Aliases: A230106A15Rik antibody, BCNS antibody, FLJ26746 antibody, FLJ42602 antibody, Holoprosencephaly 7 antibody, HPE7 antibody, mes antibody, NBCCS antibody, OTTHUMP00000021709 antibody, OTTHUMP00000021710 antibody, Patched antibody, Patched (Drosophila) homolog antibody, Patched 1 antibody, Patched homolog (Drosophila) antibody, Patched homolog 1 (Drosophila) antibody, Patched homolog 1 antibody, Patched protein homolog 1 antibody, Protein patched homolog 1 antibody, PTC antibody, PTC1 antibody, PTC1_HUMAN antibody, PTCH antibody, PTCH protein +12b antibody, PTCH protein +4' antibody, PTCH protein -10 antibody, PTCH protein antibody, ptch1 antibody, PTCH1 protein antibody, PTCH11 antibody, Ptch2 antibody

UniProt: Q13635

Pathways: Hedgehog Signalweg, Carbohydrate Homeostasis, Tube Formation