Patched 1 Antikörper (N-Term)
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- Target Alle Patched 1 (PTCH1) Antikörper anzeigen
- Patched 1 (PTCH1)
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Patched 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Patched/PTCH1 Antibody detects endogenous levels of total Patched/PTCH1.
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Patched/PTCH1, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product PTCH1 Primärantikörper
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anti-Patched 1 (PTCH1) (C-Term) antibody
Verified PTCH1 Reaktivität: Human, Maus ELISA, IHC, IF Wirt: Ziege Polyclonal unconjugated
anti-Patched 1 (PTCH1) antibodyPTCH1 Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Patched 1 (PTCH1) (AA 213-422) antibodyPTCH1 Reaktivität: Maus WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Patched 1 (PTCH1) antibodyPTCH1 Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Patched 1 (PTCH1) antibodyPTCH1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Patched 1 (PTCH1) (AA 770-970) antibodyPTCH1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Patched 1 (PTCH1) (Internal Region) antibodyVerified PTCH1 Reaktivität: Human, Maus WB, ELISA, IF Wirt: Ziege Polyclonal unconjugated
anti-Patched 1 (PTCH1) (C-Term) antibodyPTCH1 Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Patched 1 (PTCH1) (AA 1180-1411) antibodyPTCH1 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Patched 1 (PTCH1) (AA 841-940) antibodyPTCH1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1B7 unconjugated
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- Applikationshinweise
- WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- Patched 1 (PTCH1)
- Andere Bezeichnung
- PTCH1 (PTCH1 Produkte)
- Synonyme
- BCNS antikoerper, HPE7 antikoerper, NBCCS antikoerper, PTC antikoerper, PTC1 antikoerper, PTCH antikoerper, PTCH11 antikoerper, lep antikoerper, ptc1 antikoerper, ptc2 antikoerper, Ptch antikoerper, Ptch2 antikoerper, Ptc-1 antikoerper, XPtc1 antikoerper, patched antikoerper, patched1 antikoerper, A230106A15Rik antikoerper, Ptc antikoerper, Ptc1 antikoerper, mes antikoerper, patched 1 antikoerper, patched 1 L homeolog antikoerper, Protein patched homolog 1 antikoerper, PTCH1 antikoerper, ptch1 antikoerper, Ptch1 antikoerper, ptch1.L antikoerper, ptc-1 antikoerper
- Hintergrund
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Description: Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.
Gene: PTCH1
- Molekulargewicht
- 160kDa
- Gen-ID
- 5727
- UniProt
- Q13635
- Pathways
- Hedgehog Signalweg, Carbohydrate Homeostasis, Tube Formation
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