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Patched 1 Antikörper

PTCH1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6264047
  • Target Alle Patched 1 (PTCH1) Antikörper anzeigen
    Patched 1 (PTCH1)
    Reaktivität
    • 36
    • 25
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 32
    • 5
    • 4
    Kaninchen
    Klonalität
    • 37
    • 4
    Polyklonal
    Konjugat
    • 29
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Patched 1 Antikörper ist unkonjugiert
    Applikation
    • 27
    • 21
    • 15
    • 9
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    Patched Antibody detects endogenous levels of total Patched
    Kreuzreaktivität
    Human, Maus, Ratte (Rattus)
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human Patched
    Isotyp
    IgG
    Top Product
    Discover our top product PTCH1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC-p 1:50-1:200, IF/ICC 1:100-1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C.Stable for 12 months from date of receipt
    Haltbarkeit
    12 months
  • Target
    Patched 1 (PTCH1)
    Andere Bezeichnung
    Patched (PTCH1 Produkte)
    Synonyme
    BCNS antikoerper, HPE7 antikoerper, NBCCS antikoerper, PTC antikoerper, PTC1 antikoerper, PTCH antikoerper, PTCH11 antikoerper, lep antikoerper, ptc1 antikoerper, ptc2 antikoerper, Ptch antikoerper, Ptch2 antikoerper, Ptc-1 antikoerper, XPtc1 antikoerper, patched antikoerper, patched1 antikoerper, A230106A15Rik antikoerper, Ptc antikoerper, Ptc1 antikoerper, mes antikoerper, patched 1 antikoerper, patched 1 L homeolog antikoerper, Protein patched homolog 1 antikoerper, PTCH1 antikoerper, ptch1 antikoerper, Ptch1 antikoerper, ptch1.L antikoerper, ptc-1 antikoerper
    Hintergrund

    Description: Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.

    Gene: PTCH1

    Gen-ID
    5727
    UniProt
    Q13635
    Pathways
    Hedgehog Signalweg, Carbohydrate Homeostasis, Tube Formation
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