CD14 Antikörper (AA 20-345)
Kurzübersicht für CD14 Antikörper (AA 20-345) (ABIN7160181)
Target
Alle CD14 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 20-345
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Monocyte differentiation antigen CD14 protein (20-345AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:500,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CD14
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Andere Bezeichnung
- CD14
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Hintergrund
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Background: Coreceptor for bacterial lipopolysaccharide (PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed:20133493, PubMed:23264655). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:8612135).
Aliases: CD 14 antibody, CD_antigen=CD14 antibody, CD14 antibody, CD14 antigen antibody, CD14 Molecule antibody, CD14_HUMAN antibody, LPS-R antibody, Mo2 antibody, Monocyte differentiation antigen CD14 antibody, Monocyte differentiation antigen CD14 urinary form antibody, Monocyte differentiation antigen CD14, membrane-bound form antibody, Myeloid cell specific leucine rich glycoprotein antibody, Myeloid cell-specific leucine-rich glycoprotein antibody
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UniProt
- P08571
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Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
Target
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