Caspase 9 Antikörper (AA 113-324)
Kurzübersicht für Caspase 9 Antikörper (AA 113-324) (ABIN7146968)
Target
Alle Caspase 9 (CASP9) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 113-324
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Caspase-9 protein (113-324AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500, IF:1:50-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
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Andere Bezeichnung
- CASP9
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Hintergrund
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Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
Aliases: APAF-3 antibody, Apoptotic protease Mch-6 antibody, Apoptotic protease-activating factor 3 antibody, CASP-9 antibody, CASP9 antibody, CASP9_HUMAN antibody, Caspase 9 antibody, Caspase-9 subunit p10 antibody, ICE-LAP6 antibody, ICE-like apoptotic protease 6 antibody
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UniProt
- P55211
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Pathways
- MAPK Signalweg, RTK Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Endopeptidase Activity
Target
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