ULK1 Antikörper (AA 11-312) (FITC)

Produktnummer ABIN7140918

Der Kaninchen Polyklonal Anti-ULK1-Antikörper wurde für validiert. Er ist geeignet, ULK1 in Proben von Candida sp. zu detektieren.

Kurzübersicht für ULK1 Antikörper (AA 11-312) (FITC) (ABIN7140918)

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Reaktivität: Candida sp.

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ULK1 Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-ULK1 Antikörper (FITC)

Bindungsspezifität: AA 11-312

Kreuzreaktivität: Candida sp.

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Candida glabrata Serine/threonine-protein kinase ATG1 protein (11-312AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ULK1

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Andere Bezeichnung: ATG1

Hintergrund:

Background: Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates. Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9.

Aliases: ATG1 antibody, CAGL0L06006g antibody, Serine/threonine-protein kinase ATG1 antibody, EC 2.7.11.1 antibody, Autophagy-related protein 1 antibody

UniProt: Q6FL58

Pathways: Regulation of Cell Size, Autophagie