Ephrin B2 Antikörper (pTyr330)

Produktnummer ABIN7138984

Der Kaninchen Polyklonal anti-Ephrin B2 Antikörper (ABIN7138984) detektiert spezifisch Ephrin B2 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Ephrin B2 Antikörper (pTyr330) (ABIN7138984)

Target: Ephrin B2 (EFNB2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ephrin B2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Ephrin B2 Antikörper

Bindungsspezifität: pTyr330

Verwendungszweck: Phospho-EFNB2 (Tyr330) Antibody

Kreuzreaktivität: Maus

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Peptide sequence around phosphorylation site of tyrosine 330 (N-I-Y(p)-Y-K) derived from Human Ephrin-B2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Ephrin B2

Target: Ephrin B2 (EFNB2)

Andere Bezeichnung: EFNB2

Hintergrund:

Background: Adducins are a family of cytoskeleton proteins encoded by three genes (a, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. a- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. a- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms, however, not all variants have been fully described.

Chrencik JE,et al.( 2006) J Biol Chem,281(38):28185-28192.
Kertesz N, et al. (2006) Blood, 107(6):2330-2338.
Noren NK, et al. (2004) Proc Natl Acad Sci USA, 101(15):5583-5588.

Aliases: EFN B2 antibody, EFNB 2 antibody, Efnb2 antibody, EFNB2_HUMAN antibody, Eph related receptor tyrosine kinase ligand 5 antibody, EPH-related receptor tyrosine kinase ligand 5 antibody, ephrin B2 antibody, Ephrin-B2 antibody, EphrinB2 antibody, EPLG 5 antibody, EPLG5 antibody, Htk L antibody, HTK ligand antibody, HTK-L antibody, HTKL antibody, LERK 5 antibody, LERK-5 antibody, LERK5 antibody, Ligand of eph related kinase 5 antibody, MGC126226 antibody, MGC126227 antibody, MGC126228 antibody, OTTMUSP00000024973 antibody

UniProt: P52799

Pathways: RTK Signalweg, Regulation of Muscle Cell Differentiation