MEK2 Antikörper (pThr394)

Produktnummer ABIN7138844

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch MEK2 in WB, IHC, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MEK2 Antikörper (pThr394) (ABIN7138844)

Target: MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MEK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-MEK2 Antikörper

Bindungsspezifität: pThr394

Verwendungszweck: Phospho-MAP2K2 (Thr394) Antibody

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of threonine 394 (P-G-T(p)-P-T) derived from Human MEK-2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MEK2

Target: MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))

Andere Bezeichnung: MAP2K2

Hintergrund:

Background: Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases.

Crews C M, et al. (1992) Science. 258:478-480.
Alessi D R, et al. (1994) EMBO J. 13:1610-1619.
Rosen L B, et al. (1994) Neuron. 12:1207-1221.
Cowley S, et al. (1994) Cell. 77:841-852.

Aliases: Cardiofaciocutaneous syndrome antibody, CFC syndrome antibody, CFC4 antibody, Dual specificity mitogen activated protein kinase kinase 2 antibody, Dual specificity mitogen-activated protein kinase kinase 2 antibody, ERK activator kinase 2 antibody, FLJ26075 antibody, MAP kinase kinase 2 antibody, map2k2 antibody, MAPK / ERK kinase 2 antibody, MAPK/ERK kinase 2 antibody, MAPKK 2 antibody, MAPKK2 antibody, MEK 2 antibody, MEK2 antibody, Microtubule associated protein kinase kinase 2 antibody, Mitogen activated protein kinase kinase 2 antibody, Mitogen activated protein kinase kinase 2 p45 antibody, MKK 2 antibody, MKK2 antibody, MP2K2_HUMAN antibody, OTTHUMP00000165826 antibody, OTTHUMP00000165827 antibody, PRKMK 2 antibody, PRKMK2 antibody

UniProt: P36507

Pathways: MAPK Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling