CD40 Antikörper (pThr254)

Produktnummer ABIN7138818

Der Kaninchen Polyklonal Anti-CD40-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, CD40 in Proben von Human zu detektieren.

Kurzübersicht für CD40 Antikörper (pThr254) (ABIN7138818)

Target: CD40

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD40 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CD40 Antikörper

Bindungsspezifität: pThr254

Verwendungszweck: Phospho-CD40 (Thr254) Antibody

Kreuzreaktivität: Maus

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of threonine 254 (Q-E-T(p)-L-H) derived from Human TNFRSF5.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CD40

Target: CD40

Andere Bezeichnung: CD40

Hintergrund:

Background: Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.

Aliases: AI326936 antibody, B cell associated molecule CD40 antibody, B cell surface antigen CD40 antibody, B cell-associated molecule antibody, B-cell surface antigen CD40 antibody, Bp50 antibody, CD 40 antibody, CD40 antibody, CD40 antigen (TNF receptor superfamily member 5) antibody, CD40 antigen antibody, CD40 Molecule antibody, CD40 Molecule, TNF receptor superfamily member 5 antibody, CD40 protein antibody, CD40 type II isoform antibody, CD40L receptor antibody, CDw40 antibody, GP39 antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, MGC9013 antibody, Nerve growth factor receptor related B lymphocyte activation molecule antibody, OTTHUMP00000031699 antibody, OTTHUMP00000031700 antibody, p50 antibody, T-BAM antibody, TBAM antibody, TNF receptor superfamily member 5 antibody, TNFRSF5 antibody, TNR5_HUMAN antibody, TRAP antibody, Tumor necrosis factor receptor superfamily , member 5 antibody, Tumor necrosis factor receptor superfamily member 5 antibody, Tumor necrosis factor receptor superfamily member 5 precursor antibody, Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a antibody

UniProt: P25942

Pathways: NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints