SREBF1 Antikörper
Kurzübersicht für SREBF1 Antikörper (ABIN7119532)
Target
Alle SREBF1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- SREBF1 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- sterol regulatory element binding transcription factor 1
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IP: 1:200-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
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Andere Bezeichnung
- SREBF1
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Hintergrund
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Synonyms: Sterol regulatory element-binding protein 1 (SREBP-1)|Class D basic helix-loop-helix protein 1 (bHLHd1)|Sterol regulatory element-binding transcription factor 1|Processed sterol regulatory element-binding protein 1 Alternative names: Transcription factor SREBF1|SREBF1|BHLHD1|SREBP1
Background: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway(By similarity). Binds to the sterol regulatory element 1(SRE-1)(5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif(5'-ATCACGTGA-3') and to SRE-1(5'-ATCACCCCAC-3').
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Molekulargewicht
- 125 kDa
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Gen-ID
- 6720
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UniProt
- P36956
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Pathways
- AMPK Signaling, Caspase Kaskade in der Apoptose, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha
Target
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