Caspase 9 Antikörper (AA 141-392)
Kurzübersicht für Caspase 9 Antikörper (AA 141-392) (ABIN7112370)
Target
Alle Caspase 9 (CASP9) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 141-392
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Verwendungszweck
- CASP9 antibody
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Aufreinigung
- Protein A+G purification
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 141-392aa
Immunogen: caspase 9, apoptosis-related cysteine peptidase
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Isotyp
- IgG1
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Applikationshinweise
- WB: 1:500-1:2000, IP: 1:500-1:1000, IHC: 1:100-1:400, IF: 1:50-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
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Andere Bezeichnung
- CASP9
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Hintergrund
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Synonyms: Caspase-9 (CASP-9)|Apoptotic protease Mch-6|Apoptotic protease-activating factor 3 (APAF-3)|ICE-like apoptotic protease 6 (ICE-LAP6)|Caspase-9 subunit p35|Caspase-9 subunit p10|CASP9|MCH6
Background: Caspase 9, apoptosis-related cysteine protease(CASP9, synonyms: MCH6, APAF3, APAF-3, ICE-LAP6, CASPASE-9c)is a member of the cysteine-aspartic acid protease(caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. Caspase 9 is processed by APAF1, this step is thought to be one of the earliest in the caspase activation cascade
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Molekulargewicht
- 46 kDa, 36 kDa
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Gen-ID
- 842
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UniProt
- P55211
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Pathways
- MAPK Signalweg, RTK Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Endopeptidase Activity
Target
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