Patched 1 Antikörper (AA 1-100) (Biotin)

Produktnummer ABIN7091515

Der Kaninchen Polyklonal Anti-Patched 1-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Patched 1 in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für Patched 1 Antikörper (AA 1-100) (Biotin) (ABIN7091515)

Target: Patched 1 (PTCH1)

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Patched 1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Patched 1 Antikörper (Biotin)

Bindungsspezifität: AA 1-100

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Patched

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu Patched 1

Target: Patched 1 (PTCH1)

Andere Bezeichnung: Patched

Hintergrund:

Synonyms: Protein patched homolog 1, PTCH, PTC1, A230106A15Rik, BCNS, FLJ26746, FLJ42602, Holoprosencephaly 7, HPE7, mes, NBCCS, OTTHUMP00000021709, OTTHUMP00000021710, Patched, Patched (Drosophila) homolog, Patched 1, Patched homolog (Drosophila), Patched homolog 1 (Drosophila), Patched homolog 1, Patched protein homolog 1, PTC, PTC1, PTCH, PTCH protein +12b, PTCH protein +4', PTCH protein -10, PTCH protein, PTCH1, PTCH1 protein, PTCH11, Ptch2, , Patched / PTCH, PTC1_HUMAN.

Background: Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.

Gen-ID: 5727

UniProt: Q13635

Pathways: Hedgehog Signalweg, Carbohydrate Homeostasis, Tube Formation