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Cullin 2 Antikörper (AA 365-745) (HRP)

CUL2 Reaktivität: Human ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN705275
  • Target Alle Cullin 2 (CUL2) Antikörper anzeigen
    Cullin 2 (CUL2)
    Bindungsspezifität
    • 14
    • 9
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 365-745
    Reaktivität
    • 72
    • 40
    • 26
    • 8
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Human
    Wirt
    • 68
    • 3
    • 1
    Kaninchen
    Klonalität
    • 61
    • 11
    Polyklonal
    Konjugat
    • 36
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Cullin 2 Antikörper ist konjugiert mit HRP
    Applikation
    • 37
    • 25
    • 15
    • 14
    • 13
    • 13
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Cullin 2
    Isotyp
    IgG
    Top Product
    Discover our top product CUL2 Primärantikörper
  • Applikationshinweise
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handhabung
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Cullin 2 (CUL2)
    Andere Bezeichnung
    Cullin 2 (CUL2 Produkte)
    Hintergrund

    Synonyms: Cullin2, Cullin-2, CUL 2, MGC131970, CUL2_HUMAN.

    Background: Cullin 2 is a member of the family of human Cullin genes (CUL1, 2, 3, 4a, 4b and 5) homologous to the S. cerevisiae cdc53 gene. It is a component of E3 ubiquitin ligase complexes, including the inactive transcriptional elongation complex SIII, which mediates the ubiquitination of hypoxia-inducible factor (HIF). SIII is formed by three subunits: Elongin C, Elongin B and VHL. Cullin 2 may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.

    Gen-ID
    8453
    Pathways
    M Phase, Asymmetric Protein Localization, SARS-CoV-2 Protein Interaktom
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