BIRC3 Antikörper
Kurzübersicht für BIRC3 Antikörper (ABIN7073179)
Target
Alle BIRC3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse cIAP2
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anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 59-88), (N-Term) antibody
BIRC3 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB34025 unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 1-180) antibodyBIRC3 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 101-131), (N-Term) antibodyBIRC3 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB2213 unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 1-604) antibodyBIRC3 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 1-604) antibodyBIRC3 Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 76-245) antibodyBIRC3 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (Internal Region) antibodyVerified BIRC3 Reaktivität: Human WB, ELISA, IHC Wirt: Ziege Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 255-529) antibodyBIRC3 Reaktivität: Human WB, IF Wirt: Maus Monoclonal 1D12 unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 101-131) antibodyBIRC3 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 314-508) antibodyBIRC3 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB (M,R) 1: 500-1: 1000, IHC/IF (M,R) 1:1500-1:3000/1:750-1:1500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
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Andere Bezeichnung
- cIAP2
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Hintergrund
- Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin- protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. Protects cells from spontaneous formation of the ripoptosome, a large multi-protein complex that has the capability to kill cancer cells in a caspase dependent and caspase independent manner.
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Molekulargewicht
- 67 kDa
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Gen-ID
- 11796
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NCBI Accession
- NP_031490
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UniProt
- O08863
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades
Target
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