BIRC3 Antikörper (AA 101-131)
Kurzübersicht für BIRC3 Antikörper (AA 101-131) (ABIN3030108)
Target
Alle BIRC3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 101-131
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Verwendungszweck
- cIAP2 Antibody
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Aufreinigung
- Antigen affinity
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Immunogen
- A portion of amino acids 101-131 from the human protein was used as the immunogen for this cIAP2 antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the cIAP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the cIAP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
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Andere Bezeichnung
- cIAP2
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Hintergrund
- BIRC3 is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain.
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UniProt
- Q13489
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades
Target
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