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BIRC3 Antikörper (N-Term)

BIRC3 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB2213 unconjugated
Produktnummer ABIN390069
  • Target Alle BIRC3 Antikörper anzeigen
    BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
    Bindungsspezifität
    • 15
    • 11
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-131, N-Term
    Reaktivität
    • 64
    • 23
    • 6
    • 1
    Human
    Wirt
    • 59
    • 5
    • 2
    Kaninchen
    Klonalität
    • 61
    • 5
    Polyklonal
    Konjugat
    • 34
    • 7
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BIRC3 Antikörper ist unkonjugiert
    Applikation
    • 54
    • 34
    • 26
    • 17
    • 13
    • 13
    • 10
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This cIAP2 (BIRC3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-131 amino acids from the N-terminal region of human cIAP2 (BIRC3).
    Klon
    RB2213
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product BIRC3 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Chen, Xie, Gu, Cai, Wang, Xie, Dong, He, Zhong, Lin, Huang: "Upregulated WDR5 promotes proliferation, self-renewal and chemoresistance in bladder cancer via mediating H3K4 trimethylation." in: Scientific reports, Vol. 5, pp. 8293, (2015) (PubMed).

    Sun, Liu, Zou, Lan, Sun, Wang, Zhao, Jiang, Liu: "Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer." in: Journal of bioenergetics and biomembranes, (2015) (PubMed).

  • Target
    BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
    Andere Bezeichnung
    cIAP2 (BIRC3) (BIRC3 Produkte)
    Synonyme
    AIP1 antikoerper, API2 antikoerper, CIAP2 antikoerper, HAIP1 antikoerper, HIAP1 antikoerper, MALT2 antikoerper, MIHC antikoerper, RNF49 antikoerper, c-IAP2 antikoerper, Api1 antikoerper, Api2 antikoerper, IAP1 antikoerper, IAP2 antikoerper, MIHB antikoerper, Birc2 antikoerper, HIAP2 antikoerper, MIAP1 antikoerper, MIAP2 antikoerper, cIAP1 antikoerper, cIAP2 antikoerper, cIAP-1 antikoerper, cIAP-2 antikoerper, AW107670 antikoerper, BIRC2 antikoerper, baculoviral IAP repeat containing 3 antikoerper, baculoviral IAP repeat-containing 3 antikoerper, baculoviral IAP repeat-containing protein 3 antikoerper, inhibitor of apoptosis protein-2 antikoerper, BIRC3 antikoerper, Birc3 antikoerper, LOC100399118 antikoerper, OpmnVgp074 antikoerper
    Hintergrund
    BIRC3 is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain.
    Molekulargewicht
    68372
    Gen-ID
    330
    NCBI Accession
    NP_001156, NP_892007
    UniProt
    Q13489
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades
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