ULK1 Antikörper (AA 951-1050) (Cy3)
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- Target Alle ULK1 Antikörper anzeigen
- ULK1 (Unc-51 Like Kinase 1 (ULK1))
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Bindungsspezifität
- AA 951-1050
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ULK1 Antikörper ist konjugiert mit Cy3
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Homologie
- Cow,Pig,Horse,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ATG1/ULK1
- Isotyp
- IgG
- Top Product
- Discover our top product ULK1 Primärantikörper
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anti-Unc-51 Like Kinase 1 (ULK1) (AA 951-1050) antibody
ULK1 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) (AA 602-715) antibodyULK1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2H8 unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) (AA 400-499) antibodyULK1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) antibodyULK1 Reaktivität: Human, Maus WB, ELISA, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) (pSer556) antibodyULK1 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) (pSer556) antibodyULK1 Reaktivität: Human DB, IF Wirt: Kaninchen Polyclonal RB30585 unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) (AA 567-577) antibodyULK1 Reaktivität: Human WB, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) (AA 567-577) antibody (Alkaline Phosphatase (AP))ULK1 Reaktivität: Human WB, IF, ICC Wirt: Kaninchen Polyclonal Alkaline Phosphatase (AP)
anti-Unc-51 Like Kinase 1 (ULK1) (AA 567-577) antibody (HRP)ULK1 Reaktivität: Human WB, IF, ICC Wirt: Kaninchen Polyclonal HRP
anti-Unc-51 Like Kinase 1 (ULK1) (AA 567-577) antibody (FITC)ULK1 Reaktivität: Human WB, IF, ICC Wirt: Kaninchen Polyclonal FITC
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- Applikationshinweise
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- ULK1 (Unc-51 Like Kinase 1 (ULK1))
- Andere Bezeichnung
- ATG1/ULK1 (ULK1 Produkte)
- Hintergrund
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Synonyms: ATG1, ATG1A, UNC51, hATG1, Unc51.1, Serine/threonine-protein kinase ULK1, Autophagy-related protein 1 homolog, Unc-51-like kinase 1, ULK1, KIAA722
Background: Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA652 and RPTOR, however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation.
- Gen-ID
- 8408
- UniProt
- O75385
- Pathways
- Regulation of Cell Size, Autophagie
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