PYCARD Antikörper
Kurzübersicht für PYCARD Antikörper (ABIN7259322)
Target
Alle PYCARD Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein of human ASC / TMS1
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Isotyp
- IgG
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anti-PYD and CARD Domain Containing (PYCARD) (AA 50-195) antibody
PYCARD Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) antibodyPYCARD Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (C-Term) antibodyVerified PYCARD Reaktivität: Human WB, ELISA, IHC Wirt: Ziege Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (AA 1-120) antibodyPYCARD Reaktivität: Human ELISA, IHC, FACS, ICC Wirt: Maus Monoclonal 1C3D3 unconjugated
anti-PYD and CARD Domain Containing (PYCARD) antibodyPYCARD Reaktivität: Human WB, IHC, FACS, IHC (p) Wirt: Maus Monoclonal 3E9 unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (Internal Region) antibodyVerified PYCARD Reaktivität: Human, Maus, Ratte ELISA, IF Wirt: Ziege Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (N-Term) antibodyPYCARD Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (AA 1-149) antibodyPYCARD Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (AA 1-195) antibodyPYCARD Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) antibodyPYCARD Reaktivität: Human WB, IF, ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- IHC 1:50-1:200 IF 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- PYCARD (PYD and CARD Domain Containing (PYCARD))
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Andere Bezeichnung
- ASC / TMS1
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Hintergrund
- This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm, however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.
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Gen-ID
- 29108
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UniProt
- Q9ULZ3
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Pathways
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome
Target
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