CDC42 Antikörper
Kurzübersicht für CDC42 Antikörper (ABIN7255812)
Target
Alle CDC42 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein of human CDC42 (NP_001782.1).
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Isotyp
- IgG
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anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 25-191) antibody
CDC42 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 1-191) antibodyCDC42 Reaktivität: Human, Maus, Ratte, Hund WB, IF Wirt: Maus Monoclonal 44-CDC42 unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) antibodyCDC42 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Monoclonal 3C3 unconjugated Recombinant Antibody
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 1-191) antibodyCDC42 Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 121-138), (Middle Region) antibodyCDC42 Reaktivität: Human, Maus, Ratte, Rind (Kuh) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) antibodyCDC42 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 1-188) antibodyCDC42 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 2-188) antibodyCDC42 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 38-87) antibodyCDC42 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Affe, Huhn, Kaninchen, Pferd, Xenopus laevis, Insekten, Meerschweinchen, Avian WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) antibodyCDC42 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal unconjugated
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Applikationshinweise
- IHC 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
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Andere Bezeichnung
- CDC42
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Hintergrund
- The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20.
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Gen-ID
- 998
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UniProt
- P60953
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Pathways
- MAPK Signalweg, Microtubule Dynamics, RTK Signalweg, WNT Signalweg, T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Signaling Events mediated by VEGFR1 and VEGFR2, EGFR Downregulation, VEGF Signaling
Target
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