FOXO1 Antikörper (pSer322, pSer325)

Produktnummer ABIN7250773

Der Kaninchen Polyklonal Anti-FOXO1-Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, FOXO1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für FOXO1 Antikörper (pSer322, pSer325) (ABIN7250773)

Target: FOXO1 (Forkhead Box O1 (FOXO1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-FOXO1 Antikörper

Bindungsspezifität: pSer322, pSer325

Produktmerkmale: Phosphorylated antibody

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from human FoxO1/3 around the phosphorylation site of Ser322/S325

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FOXO1

Target: FOXO1 (Forkhead Box O1 (FOXO1))

Andere Bezeichnung: FOXO1/3

Hintergrund: FOXO1 (Forkhead Box O1) is a Protein Coding gene. Diseases associated with FOXO1 include Rhabdomyosarcoma 2, Alveolar and Rhabdomyosarcoma. Among its related pathways are Constitutive Signaling by AKT1 E17K in Cancer and Common Cytokine Receptor Gamma-Chain Family Signaling Pathways. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and chromatin binding. An important paralog of this gene is FOXO3. FOXO3 (Forkhead Box O3) is a Protein Coding gene. Diseases associated with FOXO3 include Rhabdomyosarcoma and Lung Cancer. Among its related pathways are Development IGF-1 receptor signaling and Constitutive Signaling by AKT1 E17K in Cancer. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and protein kinase binding. An important paralog of this gene is FOXO1.

Molekulargewicht:

Observed_MW: 97 kDa

Calculated_MW: 70 kDa

UniProt: Q12778, O43524

Pathways: PI3K-Akt Signalweg, Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling