AMACR Antikörper
Kurzübersicht für AMACR Antikörper (ABIN7250047)
Target
Alle AMACR Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Produktmerkmale
- Monoclonal Antibody
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Aufreinigung
- Protein A purification
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Immunogen
- Synthetic Peptide
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:100-1:300
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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Andere Bezeichnung
- AMACR
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Hintergrund
- This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
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Molekulargewicht
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Observed_MW: 42 kDa
Calculated_MW: 42 kDa
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UniProt
- Q9UHK6
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Pathways
- Monocarboxylic Acid Catabolic Process
Target
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