AMACR Antikörper (AA 323-351)
Kurzübersicht für AMACR Antikörper (AA 323-351) (ABIN3029920)
Target
Alle AMACR Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 323-351
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Verwendungszweck
- AMACR Antibody
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Aufreinigung
- Antigen affinity
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Immunogen
- A portion of amino acids 323-351 from the human protein was used as the immunogen for this AMACR antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the AMACR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the AMACR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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Andere Bezeichnung
- AMACR
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Hintergrund
- This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.
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UniProt
- Q9UHK6
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Pathways
- Monocarboxylic Acid Catabolic Process
Target
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