TLR4 Antikörper
Kurzübersicht für TLR4 Antikörper (ABIN7249750)
Target
Alle TLR4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Produktmerkmale
- Monoclonal Antibody
-
Aufreinigung
- Affinity purification
-
Immunogen
- Recombinant protein corresponding to Mouse TLR4
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- IHC 1:200-1:800
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1.8 mg/mL
-
Buffer
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- TLR4 (Toll-Like Receptor 4 (TLR4))
-
Andere Bezeichnung
- CD284
-
Hintergrund
- TLR4,also named as CD284,belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88,TIRAP and TRAF6,leading to NF-kappa-B activation,cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
-
UniProt
- Q9QUK6, Q9QX05
-
Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteine
Target
-